Startup Showcase: Vico Therapeutics Revolutionizing Rare Neurological Disorder Therapies

Introduction: Welcome to, where we bring you the most intriguing and groundbreaking startups from around the world. In this edition, we present Vico Therapeutics, a dynamic company based in Leiden, The Netherlands, that is revolutionizing the field of ribonucleic acid (RNA) modulating therapies. Join us as we dive into their remarkable journey of developing innovative treatments for rare neurological disorders.

Unleashing the Potential of RNA Modulation

At Vico Therapeutics, their mission is clear: to unlock the immense potential of RNA modulation to address the urgent needs of patients suffering from rare neurological disorders. Harnessing the power of cutting-edge science, the company is committed to developing transformative therapies that target the underlying causes of these debilitating conditions.

Pioneering Solutions for Rare Neurological Disorders

Under the leadership of its visionary founders, Luc Dochez, Josh Mandel-Brehm, Judith van Deutekom, and Gail Mandel, Vico Therapeutics is spearheading pioneering research and development efforts. The company’s initial focus lies on three specific areas: spinocerebellar ataxia (SCA), Huntington’s disease (HD), and Rett syndrome (RTT). By addressing the root causes of these disorders, Vico Therapeutics aims to enhance the quality of life for countless individuals and their families.

Targeting Spinocerebellar Ataxia (SCA)

SCA, a subgroup of hereditary ataxia, poses significant challenges for both patients and healthcare providers. Vico Therapeutics is dedicated to providing a viable therapy option for this condition by targeting the underlying RNA dysregulation. Their innovative approach aims to restore the proper function of affected cells, thereby mitigating the progression of this debilitating disorder.

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Advancing Huntington’s Disease (HD) Treatments

Huntington’s disease, a devastating neurodegenerative disorder, affects millions worldwide. Vico Therapeutics is at the forefront of developing groundbreaking therapies that target the genetic abnormalities causing HD. By utilizing their RNA modulation expertise, the company strives to deliver a breakthrough treatment that can effectively alleviate the symptoms and slow down the progression of this incurable condition.

Empowering Rett Syndrome (RTT) Patients

Rett syndrome primarily affects girls and is characterized by severe neurodevelopmental impairments. Vico Therapeutics recognizes the urgent need to support individuals with RTT and their families. By developing therapies that address the underlying RNA disturbances, Vico Therapeutics is determined to provide a glimmer of hope for those affected by this rare disorder.


Vico Therapeutics stands as a shining beacon of hope in the realm of rare neurological disorder therapies. Their commitment to pushing the boundaries of RNA modulation and targeting the root causes of these conditions sets them apart. By working tirelessly to develop innovative treatments for SCA, HD, and RTT, Vico Therapeutics is transforming the lives of patients and families worldwide.



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